BioE Graduate Seminars

Event Introduction

Biofabrication Strategies for Tissue and Tissue Model Engineering

Abstract

Over the last decades, the fabrication of three-dimensional (3D) tissues has become commonplace. However, conventional 3D fabrication techniques are limited in their capacity to produce complex tissue constructs with the required precision and controllability that are needed to replicate biologically relevant tissues.

To this end, 3D bioprinting offers great versatility in the fabrication of biomimetic volumetric tissues that are structurally and functionally relevant. The technology enables precise control of the composition, spatial distribution, and architecture of bioprinted constructs facilitating the recapitulation of the delicate shapes and structures of targeted organs and tissues.

This talk will discuss our recent efforts in developing a series of advanced 3D bioprinting strategies along with various cytocompatible bioink formulations. These platform technologies, when combined with microfluidic systems, are likely to provide new opportunities in constructing functional tissues to facilitate regeneration and microtissue models for promoting personalized medicine.

About the speaker

Dr. Zhang is an Assistant Professor in the Department of Medicine at Harvard Medical School and Associate Bioengineer in the Division of Engineering in Medicine at the Brigham and Women’s Hospital. Dr. Zhang is directing the Laboratory of Engineered Living Systems, where the research is focused on innovating medical engineering technologies, including 3D bioprinting, organs-on-chips, microfluidics, and bioanalysis, to recreate functional tissues and their biomimetic models for applications in regenerative medicine and personalized medicine.

He is an author of >205 peer-reviewed publications and his scientific contributions have been recognized by >40 international, national and regional awards.